Lyophilized hgf preparation

Details Lyophilized hgf preparation Lyophilized hgf preparation

A - Human Necessities

61

K

A61K 38/22 (2006.01) A61K 9/14 (2006.01) A61K 9/19 (2006.01) A61K 38/18 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2375779

Freeze dried preparations containing hepatocyte growth factor (HGF), a stabilizer such as arginine or lysine, sodium chloride and a buffer. These preparations, which are produced from an aqueous solution containing less than 5 mg/mL of HGF and/or to be used in producing an aqueous solution containing less than 5 mg/mL of HGF, are excellent in storage stability.

L'invention porte sur des préparations lyophilisées contenant du HGF ( facteur de croissance des hépatocytes), un stabilisant tel que de l'arginine ou de la lysine, du chlorure de sodium et un tampon. Ces préparations, qui sont produites à partir d'une solution aqueuse à moins de 5 mg/ml de HGF et/ou servent à produire une solution aqueuse à moins de 5 mg/ml de HGF présentent une excellente stabilité de stockage.

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