Lyophilized native gamma globulin preparation for...

Details Lyophilized native gamma globulin preparation for... Lyophilized native gamma globulin preparation for...

A - Human Necessities

61

K

167/139

A61K 39/395 (2006.01) A61K 35/14 (2006.01) C07K 16/06 (2006.01)

Patent

CA 1093965

18/12 LYOPHILIZED NATIVE GAMMA GLOBULIN PREPARATION FOR INTRAVENOUS ADMINISTRATION ABSTRACT OF THE DISCLOSURE Freeze-drying of an aqueous solution of human native gamma globulin having an anticomplementary activity of 20 (C'H5O) or less in the presence of 0.06 to 0.26 part by weight of a neutral inorganic salt for 1 part by weight of the gamma globulin gives an immunoactive lyophilized native gamma globulin preparation which has undergone neither increase in anticomplementary activity nor deter- ioration in antibody activity during the freeze-drying and is safe for use in intravenous administration.

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