Lyophilized pharmaceutical compositions and methods for...

A - Human Necessities – 61 – K

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167/37, 167/48,

A61K 35/16 (2006.01) A61K 37/02 (1980.01)

Patent

CA 1109392

Abstract of the Disclosure Reconstitution of freeze-dried materials, particularly pharmaceuticals or diagnostic agents, is greatly facilitated by inclusion of surface active agents, preferably non-ionic surface active agents, in the composition prior to lyophilization. Preferred are surfactants which are solid at room temperature and have HLB numbers of about 14-40, in an amount of about 0.01-20% by weight of the solids in the composition to be lyophilized.

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