Lyophilized preparation of 6-(3-dimethylaminopropionyl)...

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A61K 31/35 (2006.01) A61K 9/19 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01) A61K 47/26 (2006.01) C07D 311/92 (2006.01)

Patent

CA 2018573

A lyophilized preparation comprising 6-(3-dimethylaminopropionyl)forskolin, a buffer agent having a pH value of about 3 to about 6 when dissolved, and, as an optional ingredient, a sugar. The lyophilized preparation is excellent in resolubility and stable in both pH and residual percentage.

Préparation lyophilisée renfermant la 6-(3-diméthylaminopropionyl)forskoline, agent tampon possédant à l'état dissous un pH d'environ 3 à environ 6, et un sucre, comme ingrédient facultatif. La préparation lyophilisée est excellente du point de vue résolvabilité, et stable au niveau du pH et du pourcentage résiduel.

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