Lyophilized preparation of stabilized anthracycline compounds

Details Lyophilized preparation of stabilized anthracycline compounds Lyophilized preparation of stabilized anthracycline compounds

A - Human Necessities

61

K

A61K 31/704 (2006.01) A61K 9/19 (2006.01) A61K 47/18 (2006.01) A61K 47/20 (2006.01) A61P 35/00 (2006.01) C07H 15/252 (2006.01)

Patent

CA 2509449

A freeze-dried preparation which is a freeze-dried amrubicin preparation, contains L-cystein or a salt thereof, has a water content of 0 to about 4 wt.%, and is stable even in long-term storage; and a process for producing the preparation. The preparation is useful as a chemotherapeutic agent for cancers.

L'invention concerne une préparation lyophilisée formant une préparation d'amrubicine lyophilisée qui contient de la L-cystéine ou un sel de celle-ci, présente une teneur en eau comprise entre 0 et environ 4 % en poids, et est stable au stockage de longue durée ; et un procédé de production de cette préparation. Cette préparation est utile comme agent chimiothérapeutique pour traiter des cancers.

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