Lyophilized thioxanthenone antitumor agents

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/38 (2006.01) A61K 9/19 (2006.01) A61K 31/382 (2006.01) A61K 31/67 (2006.01) A61K 47/12 (2006.01) A61K 47/26 (2006.01) A61K 47/02 (2006.01)

Patent

CA 2232444

Disclosed are reconstituted lyophilized formulations for the treatment of mammalian tumors comprising a thioxanthenone antitumor agent in combination with mannitol or sucrose as a stabilizer in a lactate buffer.

La présente invention concerne des formulations lyophilisées reconstituées destinées au traitement de tumeurs de mammifères. Ces formulations comprennent un agent antitumoral, à savoir la thioxanthénone, combinée à un stabilisant, en l'occurrence le mannitol ou le saccharose, dans un tampon de lactate.

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