Lysoganglioside derivitives

Details Lysoganglioside derivitives Lysoganglioside derivitives

C - Chemistry, Metallurgy

07

H

167/199, 260/230

C07H 15/04 (2006.01) A61K 31/70 (2006.01) C07H 15/10 (2006.01)

Patent

CA 2004189

Abstract of the Disclosure Novel N-acyl-lysogangliosides obtained from gangliosides by deacyation of the ceramide group, wherein the acyl group is derived from an aliphatic acid having from 2 to 24 carbon atoms, substituted by one or more polar groups. The N-acyl-lysogangliosides of the invention exhibit an inhibiting action on protein-kinase C activation and, thus, can be utilized in therapies for various pathologies of the nervous system.

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