Lysophosphatidic acid acetyltransferases

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) C12N 9/10 (2006.01) C12N 15/82 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2362650

An isolated nucleic acid fragment encoding an LPAAT isozyme is disclosed. Construction of a chimeric gene encoding all or a portion of the LPAAT isozyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the LPAAT isozyme in a transformed host cell is also disclosed.

Cette invention porte sur un fragment isolé d'acide nucléique codant une isoenzyme LPAAT (acide lysophonsphatidique acyltransférase). L'invention concerne également la construction d'un gène chimère codant tout ou partie de l'isoenzyme LPAAT selon une orientation <= sens >= ou anti-sens, l'expression du gène chimère donnant lieu à des modifications de la concentration d'isoenzyme LPAAT dans une cellule hôte transformée.

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