Lysyl oxidase synthetic polynucleotides

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/53 (2006.01) A61K 31/70 (2006.01) A61K 38/44 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07K 14/78 (2006.01) C07K 16/40 (2006.01) C07K 17/02 (2006.01) C12N 9/06 (2006.01) C12P 21/00 (2006.01) C12Q 1/26 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2261572

This invention relates to synthetic polynucleotides which encode lysyl oxidase, lysyl oxidase like molecules or variants of these species. The synthetic polynucleotides of the invention permit the expression of functional lysyl oxidase, lysyl oxidase like molecules or variants of these species, typically in good yield. The invention also relates to recombinant DNA molecules containing these, synthetic polynucleotides, to cells containing them and to uses of the expression products.

Polynucléotides synthétiques codant la lysyle oxydase, des molécules de type lysyle oxydase ou des variantes de ces espèces chimiques. Ces polynucléotides synthétiques permettent l'expression de lysyle oxydase fonctionnelle, de molécules de type lysyle oxydase ou des variantes de ces espèces, avec une productivité généralement bonne. L'invention concerne également des molécules d'ADN recombiné contenant ces polynucléotides synthétiques, des cellules les contenant et l'utilisation des produits d'expression.

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