M. haemolytica outer membrane protein plpe as a vaccine or...

Details M. haemolytica outer membrane protein plpe as a vaccine or... M. haemolytica outer membrane protein plpe as a vaccine or...

A - Human Necessities

61

K

A61K 39/02 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) C07K 1/00 (2006.01) C07K 2/00 (2006.01)

Patent

CA 2516661

Vaccines and methods against M. haemolytica infections in cattle. The vaccine compositions include a recombinant outer membrane protein of M. haemolytica designated PlpE and/or subunits thereof, alone or in combination with other antigenic components, and a carrier or diluent. The methods involve administering an effective immunizing amount of the vaccines to susceptible bovine.

L'invention concerne des vaccins et des méthodes contre les infections à M. haemolytica chez le boeuf. Les compositions vaccinales comprennent une protéine de membrane externe de M. haemolytica appelée PlpE et/ou des sous-unités de cette protéine, seule(s) ou en combinaison avec d'autres composants antigéniques, ainsi qu'un excipient ou un diluant. Les méthodes consistent à administrer une dose immunisante efficace de ces vaccins à un bovin présentant un risque d'infection.

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