M. tuberculosis chaperonin 10 and uses thereof

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/711 (2006.01) A61K 39/00 (2006.01) A61K 39/04 (2006.01) A61K 39/39 (2006.01) A61P 31/04 (2006.01) C07K 14/35 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2429897

The invention relates to the use of cpn 10 from Mycobacterium tuberculosis, or functionally equivalent molecules of fragments thereof, in the prevention and/or treatment of allergic conditions such as asthma, rhinitis/hay fever, eczema and anaphylaxis, which conditions are associated with an underlying Th2 cell over-reactivity, or cancerous conditions.

L'invention concerne l'utilisation de cpn 10 provenant du bacille tuberculeux ou de molécules fonctionnellement équivalentes de fragments de ceux-ci, pour la prévention et/ou le traitement de conditions allergiques comme l'asthme, la rhinite/le rhume des foins, l'eczéma et l'anaphylaxie. Ces conditions sont associées à une réactivité excessive sous-jacente de cellule Th2 ou de conditions cancéreuses.

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