Machine perfusion solution for organ and biological tissue...

Details Machine perfusion solution for organ and biological tissue... Machine perfusion solution for organ and biological tissue...

A - Human Necessities

01

N

A01N 1/02 (2006.01)

Patent

CA 2424058

Machine perfusion solutions for the preservation of organs and biological tissues prior to implantation, including a prostaglandin having vasodilatory, membrane stabilizing, platelet aggregation prevention upon reperfusion, and complement activation inhibitory properties, a nitric oxide donor, a glutathione-forming agent, and an oxygen free radical scavenger.

La présente invention concerne des solutions de perfusion pour machines de perfusion, qui sont destinées à conserver les organes et tissus biologiques préalablement à leur implantation, lesquelles solutions comprennent : une prostaglandine possédant des propriétés de vasodilatation, de stabilisation membranaire, de prévention de l'agrégation plaquettaire lors de la reperfusion et d'inhibition de l'activation du complément ; un donneur d'oxyde nitrique ; un agent de formation de glutathione ; et un capteur des radicaux libres de l'oxygène.

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