C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/08 (2006.01) A61K 31/395 (2006.01) A61K 31/404 (2006.01) A61K 31/422 (2006.01) A61K 31/4427 (2006.01) A61P 25/28 (2006.01) C07D 273/02 (2006.01) C07D 291/08 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 419/12 (2006.01)
Patent
CA 2450167
The present invention is macrocycles of the formula (X): for treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme for the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
L'invention concerne des macrocycles de formule (X): destinés au traitement de la maladie d'Alzheimer et d'autres maladies semblables. Ces composés comprennent des inhibiteurs d'enzyme bêta-secrétase pour le traitement de la maladie d'Alzheimer et d'autres maladies caractérisées par le dépôt de peptide A bêta chez un mammifère. Les composés de l'invention sont utiles dans des compositions pharmaceutiques et dans des méthodes de traitement permettant de réduire la formation de peptide A bêta.
Beck James P.
Jacobs Jon S.
Pulley Shon R.
Tenbrink Ruth E.
Elan Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
Pharmacia & Upjohn Company
Pharmacia & Upjohn Company Llc
LandOfFree
Macrocycles useful in the treatment of alzheimer's disease does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Macrocycles useful in the treatment of alzheimer's disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Macrocycles useful in the treatment of alzheimer's disease will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1776140