Macrocyclic amide and urea immunomodulators

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 19/01 (2006.01) A61K 31/70 (2006.01) C07D 498/18 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2156065

Immunomodulatory macrocyclic compounds having formula (I) and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, as well as pharmaceutical compositions containing the same, which possess immunosuppressive, antimicrobial, antifungal, antiviral antiinflammatory and antiproliferative activity, as well as the ability to reverse chemotherapeutic drug resistance.

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