C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 267/22 (2006.01) A61K 31/33 (2006.01) A61P 25/28 (2006.01) C07D 225/04 (2006.01)
Patent
CA 2535337
The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the beta-secretase enzyme is involved.
L'invention concerne des composés qui sont des inhibiteurs de l'enzyme béta-secrétase et utiles dans le traitement ou la prévention de maladies dans lesquelles l'enzyme béta-secrétase est impliquée, telles que la maladie d'Alzheimer. L'invention concerne également des compositions pharmaceutiques renfermant ces composés et l'utilisation de ceux-ci et des compositions dans la prévention ou le traitement de telles maladies dans lesquelles l'enzyme béta-secrétase est impliquée.
Coburn Craig
Stachel Shawn J.
Vacca Joseph P.
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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