C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 267/22 (2006.01) A61K 31/33 (2006.01) A61P 25/28 (2006.01) C07D 273/02 (2006.01)
Patent
CA 2512111
The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the beta-secretase enzyme is involved.
La présente invention concerne des composés qui sont des inhibiteurs de l'enzyme bêta-secrétase et qui sont utilisés pour traiter ou prévenir des maladies impliquant l'enzyme bêta-secrétase, telles que la maladie d'Alzheimer. La présente invention concerne également des compositions pharmaceutiques comprenant ces composés et l'utilisation de ces composés et de ces compositions pour prévenir ou traiter des maladies impliquant l'enzyme bêta-secrétase.
Coburn Craig A.
Stachel Shawn J.
Vacca Joseph P.
Merck And Co. Inc.
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
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