C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 273/02 (2006.01) A61K 31/395 (2006.01) A61P 25/28 (2006.01) C07D 245/06 (2006.01) C07D 291/08 (2006.01)
Patent
CA 2590664
The invention relates to novel macrocyclic compounds of the formula in which R1, R3, V1, V2, X1, X2, Y, Z, Ar, AA and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16, 17 or 18, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them.
L'invention concerne de nouveaux composés macrocycliques de formule (I), dans laquelle R1, R3, V1, V2, X1, X2, Y, Z, Ar, AA et n sont tels que définis dans la description, le nombre d'atomes de noyau compris dans le noyau macrocyclique étant compris entre 14 et 18, sous forme de base libre ou sous forme de sel d'addition acide. L'invention concerne également leur préparation, leur utilisation comme médicaments et des médicaments les contenant.
Lerchner Andreas
Machauer Rainer
Simic Oliver
Tintelnot-Blomley Marina
Fetherstonhaugh & Co.
Novartis Ag
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