Macrocyclic compounds and novel method of treatment

Details Macrocyclic compounds and novel method of treatment Macrocyclic compounds and novel method of treatment

C - Chemistry, Metallurgy

07

H

C07H 19/01 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) C07D 498/18 (2006.01) C07D 498/22 (2006.01)

Patent

CA 2065425

2065425 9104025 PCTABS00003 Compounds of formula (I), wherein R1 and R2 independently represent H or OH, or a second carbon-carbon bond; R3 represents optionally substituted methyl, ethyl or propyl; R4 represents H; R5 and R6 represent a second carbon-carbon bond; R7 represents H or OH; R8 represents OCH3; R9 represents OH or OCH3; X and Y independently represent O or (H, OH); n represents 1 or 2; and in addition some of the substituents form rings with each other; with various provisos; are indicated in the treatment of immunodepression. A number of novel compounds of formula (I) are also provided.

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