Macrocyclic compounds as antiviral agents

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/12 (2006.01) A61K 38/12 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2652219

The present invention relates to macrocyclic compounds of formula (I): wherein W, n, R1, Ra, Rb, R3, R4, M, Z, ring A and ring B are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.

La présente invention concerne des composés macrocycliques de formule (I) : où W, n, R1, Ra, Rb, R3, R4, M, Z, le cycle A et le cycle B sont tels que définis dans l'invention, ainsi que des sels de qualité pharmaceutique desdits composés, des compositions pharmaceutiques les incluant et leur application au traitement prophylactique ou thérapeutique d'une infection par le virus de l'hépatite C.

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