C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/12 (2006.01) A61K 38/12 (2006.01) A61P 31/00 (2006.01)
Patent
CA 2652219
The present invention relates to macrocyclic compounds of formula (I): wherein W, n, R1, Ra, Rb, R3, R4, M, Z, ring A and ring B are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.
La présente invention concerne des composés macrocycliques de formule (I) : où W, n, R1, Ra, Rb, R3, R4, M, Z, le cycle A et le cycle B sont tels que définis dans l'invention, ainsi que des sels de qualité pharmaceutique desdits composés, des compositions pharmaceutiques les incluant et leur application au traitement prophylactique ou thérapeutique d'une infection par le virus de l'hépatite C.
Di Francesco Maria Emilia
Nizi Emanuela
Pace Paola
Summa Vincenzo
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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