Macrocyclic compounds as antiviral agents

C - Chemistry – Metallurgy – 07 – K

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C07K 5/08 (2006.01) A61K 38/06 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2654884

The present invention relates to macrocyclic compounds of formula (I): wherein W, n, m, R1, R2, R3, R4, R5, Ra, M, Z and ring B are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical co mposit ions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.

La présente invention concerne à des composés macrocycliques de formule (I) : dans laquelle W, n, m, R1, R2, R3, R4, R5, Ra, M, Z et le cycle B sont définis ici, ainsi que leurs sels pharmaceutiquement acceptables, des compositions pharmaceutiques qui les comprennent et leur utilisation pour le traitement ou la prévention d'une infection par le virus de l'hépatite C.

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