C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/495 (2006.01) A61P 31/12 (2006.01) C07D 209/00 (2006.01) C07D 245/00 (2006.01) C07K 5/08 (2006.01)
Patent
CA 2560897
The embodiments provide macrocylic compounds, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
La présente invention concerne des composés représentés par les formules générales (I à XIX), ainsi que des compositions, et notamment des compositions pharmaceutiques à base d'un composé de l'invention. L'invention concerne également un procédé permettant de traiter des infections flavivirales, hépatite C comprise, ainsi que la fibrose hépatique, en administrant à l'individu atteint une quantité suffisante d'un composé ou d'une composition de l'invention.
Andrews Steven W.
Blatt Lawrence M.
Condroski Kevin R.
Doherty George A.
Jiang Yutong
Intermune Inc.
Smart & Biggar
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