Macrocyclic compounds useful as bace inhibitors

Details Macrocyclic compounds useful as bace inhibitors Macrocyclic compounds useful as bace inhibitors

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/395 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) C07D 245/04 (2006.01) C07D 271/12 (2006.01) C07D 401/12 (2006.01) C07D 413/14 (2006.01) C07D 498/08 (2006.01)

Patent

CA 2657280

The invention relates to novel macrocyclic compounds of the Formula (I) in which all of the variables are as defined in the specification, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them.

L'invention concerne de nouveaux composés macrocycliques représentés par la Formule (I) dans laquelle toutes les variables sont telles que définies dans la description, sous forme de base libre ou sous une forme de sel d'addition avec un acide ; elle concerne également la préparation de ces composés, leur utilisation comme médicaments et les médicaments les comprenant.

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