Macrocyclic indole derivatives useful as hepatitis c virus...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 513/18 (2006.01) A61K 31/55 (2006.01) A61P 31/14 (2006.01) C07D 515/18 (2006.01)

Patent

CA 2729307

Inhibitors of HCV replication of formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein R1, R2, R4, R5, R6 and R7 have the meaning defined in the claims. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.

La présente invention concerne des inhibiteurs de la réplication du VHC de formule (I) comprenant des formes stéréochimiquement isomères, ainsi que leurs sels, leurs hydrates, et leurs solvats, où R1, R2, R4, R5, R6 et R7 ont la même signification que celle définie dans les revendications. La présente invention concerne également des procédés de préparation desdits composés, des compositions pharmaceutiques les contenant et leur utilisation dans le traitement du VHC.

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