C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/08 (2006.01) A61K 31/407 (2006.01) A61P 31/14 (2006.01) C07D 513/08 (2006.01)
Patent
CA 2710644
The present invention relates to inhibitors of HCV replication of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, formula (I), wherein R1; R3; and R4 have the meaning de- fined in the claims. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV thera- py.
La présente invention concerne des inhibiteurs de la réplication du VHC de formule (I), les formes N-oxyde, les sels d'addition pharmaceutiquement acceptables, les amines quaternaires et les formes stéréochimiquement isomériques de ceux-ci, formule (I), dans laquelle R1, R3 et R4 ont les significations définies dans les revendications. La présente invention concerne également des procédés pour préparer lesdits composés, des compositions pharmaceutiques les contenant et leur utilisation dans la thérapie contre le VHC.
Hu Lili
Nyanguile Origene
Raboisson Pierre Jean-Marie Bernard
Tahri Abdellah
Vendeville Sandrine
Gowling Lafleur Henderson Llp
Tibotec Pharmaceuticals
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