Macrocyclic inhibitors of hepatitis c virus ns3 serine protease

Details Macrocyclic inhibitors of hepatitis c virus ns3 serine protease Macrocyclic inhibitors of hepatitis c virus ns3 serine protease

C - Chemistry, Metallurgy

07

K

C07K 5/06 (2006.01) A61P 31/22 (2006.01)

Patent

CA 2701787

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such com- pounds as well as methods of using them to treat disorders associated with the HCV protease.

L'invention concerne de nouveaux composés qui possèdent une activité inhibitrice de la protéase du virus de l'hépatite C ainsi que des procédés pour préparer de tels composés. Dans un autre mode de réalisation, l'invention décrit des compositions pharmaceutiques comprenant de tels composés ainsi que des procédés les utilisant pour traiter des troubles associés à la protéase du virus de l'hépatite C.

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