Macrocyclic lactone drug delivery system

Details Macrocyclic lactone drug delivery system Macrocyclic lactone drug delivery system

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 31/365 (2006.01)

Patent

CA 2755753

Disclosed is a drug delivery system from which a macrocyclic lactone can be released with a desirable zero order release profile. The system is based on the use of thermoplastic polymers, and particularly of polyethylene vinyl acetate copoly-mers (EVA). The drug delivery system of the invention comprises a solid non-porous reservoir in which the macrocyclic lactone is contained, preferably in a concentration well above the saturation concentration, and a non-porous skin covering the reservoir not initially loaded with the drug. The system is preferably in the form of a rod, wherein the core and the skin are concentric, and the end surfaces of the rod are not skin-covered.

La présente invention concerne un système de relargage de médicament à partir duquel une lactone macrocyclique peut être libérée avec un profil de libération souhaité dordre zéro. Le système est basé sur lutilisation de polymères thermoplastiques, et particulièrement de copolymères de léthylène et de lacétate de vinyle (EVA). Le système de relargage de médicament de linvention comprend un réservoir solide non poreux dans lequel la lactone macrocyclique est contenue, de préférence en concentration bien au-dessus de la concentration de saturation, et une enveloppe non poreuse recouvrant le réservoir non chargé de médicament au départ. Le système se présente de préférence sous la forme dun bâtonnet, le cur et lenveloppe étant concentriques, et les surfaces dextrémité du bâtonnet nétant par recouvertes par lenveloppe.

Affiliated with

Also associated with

Rating

Macrocyclic lactone drug delivery system does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Macrocyclic lactone drug delivery system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Macrocyclic lactone drug delivery system will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1653694