Macrocyclic metal complexes containing fluorine

Details Macrocyclic metal complexes containing fluorine Macrocyclic metal complexes containing fluorine

C - Chemistry, Metallurgy

07

F

C07F 5/00 (2006.01) A61K 49/00 (2006.01) A61K 49/04 (2006.01) C07D 257/02 (2006.01) G01R 33/28 (2006.01) G01R 33/48 (2006.01)

Patent

CA 2163643

The invention relates to new fluorine-containing macrocyclic metal complexes that consist of a complexing agent of formula I and at least one metal ion of an element of atomic numbers 21-29, 42, 44 or 57-83 Image (I), in which n, R1, R2, R3 and A have a different meaning, agents containing these compounds, their use as NMR and x-ray diagnostic agents as well as process for the production of these compounds and agents.

L'invention concerne de nouveaux complexes métalliques macrocycliques fluorés comprenant un complexant de formule (I) et au moins un ion métal d'un élément de numéro atomique compris dans les plages 21 à 29, 42, 44 ou 57 à 83, formule dans laquelle n, m, R<1>, R<2>, R<3> et A ont des notations différentes, des agents renfermant ces composés, leur utilisation comme agents de diagnostic RMN ou aux rayons X, ainsi qu'un procédé de fabrication de ces composés et de ces agents.

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