C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) A61K 38/05 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61P 31/14 (2006.01) C07K 5/02 (2006.01) C07K 5/062 (2006.01) C07K 5/065 (2006.01) C07K 5/087 (2006.01) C07K 5/107 (2006.01) C07K 7/02 (2006.01) C07K 14/18 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2406532
The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.
La présente invention porte sur de nouveaux composés macrocycliques ayant une activité inhibitrice contre la protéase du virus de l'hépatite C, ainsi que sur des procédés de préparation de ces composés. Selon une autre réalisation, l'invention porte sur des compositions pharmaceutiques comprenant ces macrocycles, ainsi que sur leurs procédés d'utilisation dans le traitement de pathologies associées à la protéase du virus de l'hépatite C.
Arasappan Ashok
Chan Tin-Yau
Chen Kevin X.
Ganguly Ashit K.
Girijavallabhan Viyyoor M.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
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