Macrocyclic peptides active against the hepatitis c virus

Details Macrocyclic peptides active against the hepatitis c virus Macrocyclic peptides active against the hepatitis c virus

C - Chemistry, Metallurgy

07

K

C07K 5/08 (2006.01) A61K 38/06 (2006.01) A61P 31/12 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2536182

Compounds of formula I: wherein D, R4, R3, L0, L1, L2, R2 and RC are defined herein; or a pharmaceutically acceptable salt thereof, useful as inhibitors of the HCV NS3 protease.

Cette invention se rapporte à des composés représentés par la formule (I) : dans laquelle D, R?4¿, R?3¿, L?0¿, L?1¿, L?2¿, R?2¿ et R<SP>C</SP> sont définis dans les pièces descriptives de la demande ; ou à un sel pharmaceutiquement acceptable de ces composés, utiles comme inhibiteurs de la NS3 protéase du virus de l'hépatite C.

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