Macrocyclic peptides active against the hepatitis c virus

Details Macrocyclic peptides active against the hepatitis c virus Macrocyclic peptides active against the hepatitis c virus

C - Chemistry, Metallurgy

07

K

C07K 5/08 (2006.01) A61K 38/06 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2549851

Compounds of formula (I): wherein R1, R2, X,R3, D, and the dotted line b are as defined herein; or a pharmaceutically acceptable salt or ester thereof, are useful as inhibitors of the HCV NS3 protease.

Cette invention se rapporte à des composés représentés par la formule (I) ; dans laquelle R?1¿, R?2¿, X, R?3¿, D et la lignée en pointillé b sont définis dans les pièces descriptives de la demande ; ou à des sels ou esters de ces composés, acceptables sur le plan pharmaceutique, qui sont utiles comme inhibiteurs de la VHC NS3 protéase.

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