C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/18 (2006.01) A61K 31/439 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2667071
The present invention is directed to compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
L'invention concerne des composés de la formule (I) inhibiteurs de l'enzyme bêta-secrétase et utiles dans le traitement de maladies dans lesquelles l'enzyme bêta-secrétase est impliquée, comme la maladie d'Alzheimer. L'invention concerne également des compositions pharmaceutiques comportant ces composés, et l'utilisation de ces composés et compositions dans le traitement de maladies dans lesquelles l'enzyme bêta-secrétase est impliquée.
Holloway M. Katharine
Moore Keith P.
Nantermet Philippe G.
Stauffer Shaun R.
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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