Macrocyclic thioether ligands and their use as intermediates...

Details Macrocyclic thioether ligands and their use as intermediates... Macrocyclic thioether ligands and their use as intermediates...

C - Chemistry, Metallurgy

07

D

C07D 341/00 (2006.01) A61K 51/10 (2006.01) C07D 345/00 (2006.01) C07D 409/12 (2006.01) C07F 9/547 (2006.01) C07F 9/6578 (2006.01) C07F 9/80 (2006.01) A61K 49/02 (1990.01)

Patent

CA 2105872

2105872 9216520 PCTABS00016 1,4,7-Trithiacyclononane (9S3) and related compounds of formula (I), where one T is S or Se or Te, another T is S or Se or Te and the third T is S, Se, Te, >PX or >AsX, X being a univalent atom or group, and where A1 is -C2H4- or (a), or -C3H6-, A2 is -C2H4- or (a), and A3 is -C2H3R- or (b), or except when A1 is -C3H6-, -C3H5R-, where R is alkyl or substituted alkyl or, if the third T contains P or As, R may also be H, may be substituted with a linker group which can bind to a substrate such as a protein and which itself retains co-ordinating functionality to chelate a radionuclide for diagnosis or therapy.

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