Macrolide antibiotics

C - Chemistry – Metallurgy – 12 – P

Patent

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195/101, 260/230

C12P 19/62 (2006.01) C07H 17/08 (2006.01)

Patent

CA 1174994

ABSTRACT Novel macrolides of formula (I): Image (I) where Q is -CHO or -CH2OH and Y is hydroxyl or a mycarosyloxy group; and salts or esters thereof; can be prepared by the sub- merged aerobic cultivation of Streptomyces fradiae ATCC 31669 and are of value in the chemotherapy of microbial infections in warm blooded animals and as intermediates in the preparation of other closely related macrolide antibitotics.

381721

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