Macrolide antibiotics from micromonospora

C - Chemistry – Metallurgy – 12 – P

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260/230, 195/89,

C12P 19/60 (2006.01) A23K 1/17 (2006.01) A61K 35/74 (2006.01) C07H 17/08 (2006.01) C12P 1/06 (2006.01)

Patent

CA 1125203

NOVEL MACROLIDE ANTIBIOTIC FROM MICROMONOSPORA Abstract of the disclosure: A novel microorganism species belonging to the genus Micromonospora, i.e. Micromonospora sp. A 11725 is found to be capable of producing novel macrolide anti- biotics A 11725 I, A 11725 II and A 11725 III. Novel antibiotics A 11725 Ia and A 11725 IIa are also found to be derived by chemical modification of the antibiotics A 11725 I and A 11725 II, respectively. All of these antibiotics or salts thereof exhibit excellent anti- bacterial and anti-mycoplasmal activities against various microorganisms such as Staphylococcus or Mycoplasma, and therefore useful for various purposes including medicaments.

326416

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