Macrolide compounds

C - Chemistry – Metallurgy – 07 – D

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167/202, 260/210

C07D 493/22 (2006.01) A01N 43/90 (2006.01) C07H 19/01 (2006.01)

Patent

CA 1282064

Abstract: Compounds are described of the formula Image (I) and salts thereof, wherein R1 is methyl, ethyl or isopropyl; R2 is -H, or a group -OR5 (wherein -OR5 is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms); and R3 is -H, or R2 and R3 together with the carbon atom to which they are attached represent C=CH2, C=O or C=NOR6 (where R6 is -H, alkyl or alkenyl and the C=NOR6 is in the E configuration); OR4 is as defined above for OR5 and one of the symbols X represents an epoxide oxygen atom and the other represents an epoxide oxygen atom or a carbon-carbon bond. These compounds may be used for controlling insect, acarine, nematode or other pests.

531754

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