Macrolide compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 493/22 (2006.01) A01N 43/90 (2006.01) A01N 49/00 (2006.01) A61K 31/365 (2006.01) C07H 19/01 (2006.01)

Patent

CA 1304358

A B S T R A C T MACROLIDE ANTIBIOTICS Compounds are described of the formula (I) Image (I) and salts thereof, wherein R1 is a methyl, ethyl or isopropyl group; R2 is -H, -OH or substituted -OH and R3 is -H, or R2 and R3 together with the carbon atom to which they are attached represent >C=0, >C=CH2 or >C=NOR7 (where R7 is -H, alkyl, alkenyl and the group >C=NOR is in the E configuration); OR4 is -OH or substituted -OH and R6 is -H or a C1-4 alkanoyl group. These compounds may be used for controlling insect, acarine, nematode or other pests.

531752

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