Macrolide compounds

C - Chemistry – Metallurgy – 07 – D

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167/202, 260/227

C07D 493/22 (2006.01) A01N 43/90 (2006.01) C07H 17/08 (2006.01) C07H 19/01 (2006.01)

Patent

CA 1333599

Compounds of formula (1) Image (I) wherein R1 represents a methyl, ethyl or isopropyl group; Y1 is -CH2-, Y2 is -CH- and X represents Image [where R2 represents a hydrogen atom or a group OR6 (where OR6 is a hydroxy group or a substituted hydroxyl group having up to 25 carbon atoms) and R3 represents a hydrogen atom, or R2 and R3 together with the carbon atom to which they are attached represent >C=0, >C=CH2 or>C=NOR7 (where R7 represents a hydrogen atom, a C1-8 alkyl group or a C3-8 alkenyl group and the group >C=NOR7 is in the E configuration)] or -Y1-X-Y2- represents -CH= CH-CH- or -CH2-CH=C-; R4 represents a group OR6 as defined above and R5 represents a hydrogen atom, or R4 and R5 together with the carbon atom to which they are attached represent >C=0 or>C=NOR7a (where R7a is as defined above for R7); and one of R8 and R9 represents an alkoxyalkoxy grup optionally interrupted by an oxygen atom or an alkoxy group and the other represents a hydrogen atom or R 8 and R9 together with the carbon atom to which they are attached represent >C=NOR7b (where R7b is as defined above for R7), and salts thereof. These compounds may be used to control nematode, acarine, insect or other pests.

599085

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