C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 5/24 (2006.01) A61P 15/00 (2006.01)
Patent
CA 2325521
Disclosed are 3'-N-desmethyl-3'-N-susbstituted-6-O-methyl-11-deoxy-11, 12- cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
L'invention concerne des dérivés de l'érythromycine A sous forme de carbamate cyclique de 3'-N-desméthyl-3'N-6-O-méthyl substitué-11-déoxy-11,12, qui sont des antagonistes de l'hormone de libération de la lutéinostimuline (LHRH). L'invention concerne également des compositions pharmaceutiques comprenant ces composés, des techniques d'utilisation de ces composés et le procédé de fabrication de ces composés.
Bruncko Milan
Crawford Bradley W.
Dalton Christopher R.
Frey Lisa Marie
Greer Jonathon
Abbott Laboratories
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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