C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 7/06 (2006.01) A61K 31/70 (2006.01) C07D 407/06 (2006.01) C07D 407/14 (2006.01) C07H 17/04 (2006.01) C07H 17/08 (2006.01) C12P 17/08 (2006.01) C12P 19/58 (2006.01)
Patent
CA 2130044
Novel macrolides and the use thereof Abstact Compounds of the formula Image (I), wherein R1 is hydroxy, 2-hydroxyethoxy, C1-C4alkoxy, C1-C4alkanoyloxy, halogen, amino, azido, a keto, p-nitrobenzenesulfonyl or a pyranyloxy group of the formula Image wherein X is a group of the formula Image or Image wherein R3 is hydroxy, C1-C4alkanoyloxy or organic sulfonyloxy, and R4 is hydroxy or carbamoyloxy, R2 is hydrogen, hydroperoxy, hydroxy or methoxy, Y is a group of the formula Image or Image wherein R5 is hydroxy or C1-C4alkanoyloxy, and R6 and R7 each independenly of the other is hydrogen or methyl, are suitable for the preparation of a medicament for the prophylaxis and treatment of diseases that respond to the inhibition of the osteoclast proton pump.
Bindseil Kai U.
Boddien Claudia
Zeeck Axel
Fetherstonhaugh & Co.
Novartis Ag
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