Macrolides with antiinflammatory activity

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2554070

Macrolide compounds of formula (I) wherein X, R, R1, R2, R3 and R4 have the meanings as defined in the specification, pharmaceutically acceptable salts thereof, pharmaceutical compositions containing them as active ingredient and the use thereof in the treatment and prophylaxis of inflammatory diseases, are described.

L'invention concerne des composés macrolides représentés par la formule (I) dans laquelle X, R, R¿1?, R¿2?, R¿3? et R¿4? sont tels que définis dans les spécifications, des sels acceptables d'un point de vue pharmaceutique de ceux-ci, des compositions pharmaceutiques contenant ceux-ci comme ingrédients actifs, et leur utilisation dans le traitement et la prophylaxie des maladies inflammatoires.

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