Macromolecular complexes for drug delivery

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/48 (2006.01) A61K 38/28 (2006.01) A61K 47/32 (2006.01) A61K 47/36 (2006.01) A61P 1/18 (2006.01)

Patent

CA 2251008

Novel macromolecular drug complexes containing a drug, like insulin, and a polymer having a plurality of acid moieties, like carboxyl moieties or phosphonic acid moieties, are disclosed. Compositions containing the macromolecular complexes are administered to individuals suffering from a disease, and the complexes release the drug, in vivo, to treat the disease, and to reduce, eliminate, or reverse complications associated with the disease.

L'invention concerne de nouveaux complexes macromoléculaires médicamenteux renfermant un médicament, tel que l'insuline, et un polymère possédant une pluralité de fractions acides telles que des fractions carboxyle ou des fractions d'acide phosphonique. Des compositions contenant ces complexes macromoléculaires sont administrées à des individus souffrant d'une maladie, les complexes libérant le médicament, in vivo, pour traiter la maladie et atténuer, éliminer ou traiter les complications associées à la maladie.

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