A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 31/727 (2006.01) A61K 38/27 (2006.01) A61K 38/28 (2006.01) A61P 3/10 (2006.01) A61P 5/06 (2006.01)
Patent
CA 2545473
Macromoleculir drug complexes containing a protein therapeutic, like human growth hormone, and an excess stoichiometric molar amount of a polymer, like heparin, and compositions containing the same, are disclosed. Compositions containing the macro~molecular drug complexes are administered, including via pulmonary delivery, to individuals suffering from a disease or condition, and the complexes, re~lease the protein therapeutic, in vivo, to treat the disease or condition.
L'invention concerne des complexes de médicament macromoléculaire contenant un produit thérapeutique à base de protéine, telle qu'une hormone de croissance humaine, et une quantité molaire stoechiométrique excédante d'un polymère, tel que de l'héparine, ainsi que des compositions contenant ces complexes. Les compositions contenant des complexes de médicaments macromoléculaires sont administrés, notamment par administration pulmonaire, à des individus souffrant d'une maladie ou d'un trouble, et les complexes libèrent le produit thérapeutique à base de protéine, <i>in vivo</i>, afin de traiter ces maladies ou ces troubles.
Groves Michael J.
Zamiri Camellia
Smart & Biggar
The Board Of Trustees Of The University Of Illinois
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