Macrophage derived chemokine and chemokine analogs

Details Macrophage derived chemokine and chemokine analogs Macrophage derived chemokine and chemokine analogs

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) C07H 21/04 (2006.01) C07K 14/52 (2006.01) C07K 14/715 (2006.01) C07K 16/24 (2006.01) C12N 5/18 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2196691

The present invention provides purified and isolated polynucleotide sequences encoding a novel human macrophage-derived C-C chemokine designated MDC, and polypeptide analogs thereof. Also provided are materials and methods for the recombinant production of thechemokine, and purified and isolated chemokine protein, and polypeptide analogs thereof.

La présente invention concerne des séquences de polynucléotides purifiées et isolées encodant une nouvelle chémokine C-C humaine dérivée de macrophages et appelée MDC. L'invention concerne aussi des analogues polypeptidiques de celle-ci. L'invention concerne également des matériels et des procédés permettant la production par recombinaison de la chémokine, ainsi qu'une protéine de chémokine purifiée et isolée et ses analogues polypeptidiques.

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