A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 41/06 (2006.01) A61K 31/18 (2006.01) C07C 303/00 (2006.01) C07C 307/00 (2006.01) C07C 309/00 (2006.01) C07C 311/00 (2006.01) C07C 311/08 (2006.01) C07C 311/13 (2006.01) C07C 311/21 (2006.01) C07C 311/29 (2006.01) C07C 311/37 (2006.01) C07C 311/44 (2006.01)
Patent
CA 2377288
Macrophage scavenger receptor antagonists are provided. Methods of treating cardiovascular disease comprising administration of the present compounds are also provided. The present compounds inhibit lipid accumulation within macrophage-derived foam cells.
L'invention concerne des antagonistes du récepteur destructeur de macrophage. Elle concerne également des procédés servant à traiter des maladies cardio-vasculaires et consistant à administrer ces composés. Ces derniers inhibent l'accumulation des lipides à l'intérieur de cellules alvéolées dérivées de macrophages.
Franz Robert G.
Gaitanopoulos Dimitri E.
Weinstock Joseph
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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