A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/165 (2006.01) C07C 233/64 (2006.01) C07C 235/64 (2006.01)
Patent
CA 2339094
Macrophage scavenger receptor antagonists are provided. Methods of treating cardiovascular disease comprising administration of the present compounds are also provided. The present compounds inhibit lipid accumulation within macrophage-derived foam cells.
L'Invention concerne des antagonistes des récepteurs accepteurs de macrophages. L'invention concerne également des méthodes permettant de traiter les maladies cardio-vasculaires, consistant à administrer les composés de l'invention qui inhibent l'accumulation des lipides dans les cellules spumeuses dérivées des macrophages.
Franz Robert G.
Gaitanopoulos Dimitri E.
Girard Gerald R.
Weinstock Joseph P.
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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