Magainins-synthetic antimicrobial compounds

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

530/7.1, 167/103

C07K 14/46 (2006.01) A61K 38/16 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339387

A new class of broad spectrum bioactive polypeptides termed "Magainin" have been described. These peptides have a molecular weight of about 2500 or less, are highly water soluble, amphiphilic and non-hemolytic. A new method of producing antimicrobial effect by contacting a subject susceptible to microbial invasion or contamination with XPF, PGLa, an Magainin has also been described.

560650

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