Magnesium omeprazole and process for its preparation

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/12 (2006.01) C07D 401/00 (2006.01) C07F 3/02 (2006.01)

Patent

CA 2254572

Magnesium omeprazole is provided, in a form free of organic solvent residues and free of traces of more than 50 ppm of another metal ion. It is prepared by an aqueous phase process in which a solution of omeprazole in concentrated aqueous ammonia is added to a mixture of a magnesium salt and a fully ionized ammonium salt, in aqueous solution, to effect precipitation of magnesium omeprazole.

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