Magnetic iron dextran microspheres

Details Magnetic iron dextran microspheres Magnetic iron dextran microspheres

G - Physics

01

N

31/121, 167/44,

G01N 27/00 (2006.01) A61K 51/12 (2006.01) B01D 15/08 (2006.01) B01J 20/32 (2006.01) B03C 1/01 (2006.01) C02F 1/48 (2006.01) D06M 16/00 (2006.01) G01N 33/543 (2006.01) H01F 1/44 (2006.01)

Patent

CA 1217934

ABSTRACT The invention relates to colloidal sized particles composed of magnetic iron oxide (Fe3O4) coated with a polysaccharide, preferably dextran, or a derivative thereof having pendant functional groups. The particles have a magnetic moment, are electron dense, and are stable and non-aggregating under physiological conditions. They can be covalently bonded to antibodies, enzymes and other biological molecules and used to label and separate cells, cellular membranes and other biological particles and molecules by means of a magnetic field.

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