Magnetic nanoparticle compositions, and methods related thereto

H - Electricity – 01 – F

Patent

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Details

H01F 1/00 (2006.01) A61K 41/00 (2006.01) A61K 49/04 (2006.01) A61K 51/04 (2006.01) H01F 1/44 (2006.01)

Patent

CA 2534687

Disclosed are biocompatible magnetic nanoparticle compositions for various therapeutic or biological applications, and methods related thereto. Specifically, the present invention pertains to magnetic nanoparticle compositions prepared via high-pressure homogenization processes that include a turbulent flow zone. The methods of production may involve a two-step or a one-step process. The disclosed magnetic nanoparticle compositions may be useful in the treatment of the body, body part, tissue, cell, or body fluid of a subject for a variety of indications. The disclosed magnetic nanoparticle compositions may also be useful in the fixation, separation, transportation, marking or coding of targets, or energy transformation processes.

L'invention porte sur des compositions de nanoparticules magnétiques biocompatibles destinées à être utilisées dans diverses applications thérapeutiques ou biologiques et sur des procédés relatifs à ces compositions. L'invention porte notamment sur des compositions de nanoparticules magnétiques préparées par l'intermédiaire de processus d'homogénéisation haute pression comprenant une zone d'écoulement turbulente. Les procédés de production de ces compositions peuvent comprendre des processus en une ou deux étapes. Ces compositions de nanoparticules magnétiques peuvent être utiles dans le traitement de l'organisme, d'une partie de l'organisme, de tissus, de cellules ou de fluides biologiques d'un sujet pour différentes indications et peuvent être également utiles dans la fixation, la séparation, le transport, le marquage ou le codage de cibles ou dans des processus de transformation d'énergie.

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