Magnetic resonance blood pool agents

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 233/63 (2006.01) A61K 49/00 (2006.01) A61K 49/06 (2006.01) C07K 5/072 (2006.01)

Patent

CA 2271735

The present invention provides compositions comprising contrast agents capable of binding non-covalently to blood proteins. The compositions of the invention provide increased residence time of contrast agents in the vasculature, thus providing effective blood pool contrast agents. The invention also provides methods for imaging a patient comprising administering a composition of the invention to a patient and obtaining an image.

La présente invention se rapporte à des compositions comportant des agents de contraste susceptibles de se lier de manière non covalente à des protéines du sang. Ces compositions sont caractérisées par un temps de séjour accru des agents de contraste dans les vaisseaux sanguins, lesdits agents constituant des agents de contraste efficaces du pool sanguin. Cette invention se rapporte également à des procédés de formation d'images d'un patient qui consistent à administrer une telle composition à un patient et à obtenir une image.

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